Development and evaluation of Pharmacosome formulations of Mefenamic acid

Patience who suffered from menstrual pain disease is generally prescribed the non-steroidal anti-inflammatory drug (NSAIDs). Monorrhagia or another blood disorder & some gynecological disorder, which impairs body function and acts as an economic burden. Due to respective use of ACE by oral route, it may cause GI complication such bleeding, pain, perforation, abdominal swelling. To decrease side effect ACE, given topical route in promotes safety efficacy ACE. The Mefenamic Acid pharmacosomes were prepared hand shaking method technique evaluated various methods in-vitro release study, % yield, entrapment efficiency, pH formulation. system was also characterized FTIR spectrophotometer identify drug-excipients interaction. maximum efficiency found be 90%. main aim this study develop a vesicular carrier for delivery overcome problem related with route.